{"url":"https://www.thetimes.com/uk/healthcare/article/daily-multivitamin-slow-ageing-process-pbhtj3s9j?utm_source=fb&utm_medium=paid-social&utm_campaign=FY26_Times_Meta_AO_INTL_Performance_Conversions_ASC&utm_term=Meta_Multi_UK_AO_Multi_Advantage-Plus_Lifestyle&utm_content=pro_single_image_editorial_health_mar_mutivitamin-study-slow-aging_template-1&fbclid=IwdGRjcARBFqhleHRuA2FlbQEwAGFkaWQAAC_K2v--7nNydGMGYXBwX2lkCjY2Mjg1NjgzNzkAAR7TPPsVGWEzXphS59sQOUnrW8-f1HEVI3zuavDr2PlA2J0SUzLdT8qraEQ-Og_aem_Ilcu0KQ8MtHwUKfyisTeFQ","title":"Daily multivitamin slows biological ageing by months","domain":"thetimes.com","imageUrl":"https://images.pexels.com/photos/7551630/pexels-photo-7551630.jpeg?auto=compress&cs=tinysrgb&h=650&w=940","pexelsSearchTerm":"senior taking multivitamin","category":"Science","language":"en","slug":"5021f8cf","id":"5021f8cf-5468-4cb3-b313-78523b519c58","description":"A US study linked daily multivitamin use over two years to slower biological ageing in older adults.","summary":"## TL;DR\n- A US study linked daily multivitamin use over two years to slower biological ageing in older adults.\n- Participants taking multivitamins had a biological age four months younger on average than placebo takers.\n- Benefits were small, seen in two of five DNA markers, and greatest for those already ageing faster biologically.\n\n## The story at a glance\nA two-year trial by Mass General Brigham researchers found daily multivitamins slowed biological ageing markers in 958 healthy people averaging 70 years old. Participants were split into groups taking multivitamins with or without cocoa extract, or placebos; only multivitamins showed effects. The study, published in *Nature Medicine* on March 9, 2026, and funded partly by Mars Edge and US National Institutes of Health, is reported now due to its fresh peer-reviewed results.[[1]](https://www.thetimes.com/uk/healthcare/article/daily-multivitamin-slow-ageing-process-pbhtj3s9j?utm_source=fb&utm_medium=paid-social&utm_campaign=FY26_Times_Meta_AO_INTL_Performance_Conversions_ASC&utm_term=Meta_Multi_UK_AO_Multi_Advantage-Plus_Lifestyle&utm_content=pro_single_image_editorial_health_mar_mutivitamin-study-slow-aging_template-1&fbclid=IwdGRjcARBFqhleHRuA2FlbQEwAGFkaWQAAC_K2v--7nNydGMGYXBwX2lkCjY2Mjg1NjgzNzkAAR7TPPsVGWEzXphS59sQOUnrW8-f1HEVI3zuavDr2PlA2J0SUzLdT8qraEQ-Og_aem_Ilcu0KQ8MtHwUKfyisTeFQ)[[2]](https://www.nature.com/articles/d41586-026-00741-3)\n\n## Key points\n- Researchers measured ageing via five **epigenetic clocks** tracking DNA methylation patterns that change with age.\n- Multivitamins slowed ageing significantly in two mortality-linked clocks (**PCGrimAge** and **PCPhenoAge**) by **2.7 to 5.1 months** less increase over two years versus placebo.\n- Cocoa extract had no meaningful impact on any markers.\n- Greatest effects appeared in participants whose biological age exceeded their chronological age at the start.\n- Overall, multivitamin group showed biological age roughly **four months younger** after the trial compared to placebo.\n\n## Details and context\nThe trial used blood samples from the larger COSMOS study to analyse DNA changes at five sites. Epigenetic clocks estimate if cells look younger or older than a person's years; a healthy 60-year-old might read as 55 biologically. Scientists randomised groups to isolate multivitamin effects from cocoa, ruling out the latter.\n\nIndependent experts called the slowdown slight and inconsistent across markers. The two-year span limits insights into long-term health or lifespan gains. Most UK adults lack balanced diets, so supplements might fill gaps, but they are no substitute for proper eating.[[3]](https://www.theguardian.com/science/2026/mar/09/taking-multivitamin-daily-could-help-to-slow-biological-ageing-study-suggests)\n\n## Key quotes\n“The results show that multivitamin supplementation is associated with a slight reduction in the rate of biological ageing according to some of the epigenetic clocks analysed. However, this effect is not observed across all the markers evaluated, and its magnitude is small.” — Carmen Romero Ferreiro, doctor of biology at Francisco de Vitoria University.[[1]](https://www.thetimes.com/uk/healthcare/article/daily-multivitamin-slow-ageing-process-pbhtj3s9j?utm_source=fb&utm_medium=paid-social&utm_campaign=FY26_Times_Meta_AO_INTL_Performance_Conversions_ASC&utm_term=Meta_Multi_UK_AO_Multi_Advantage-Plus_Lifestyle&utm_content=pro_single_image_editorial_health_mar_mutivitamin-study-slow-aging_template-1&fbclid=IwdGRjcARBFqhleHRuA2FlbQEwAGFkaWQAAC_K2v--7nNydGMGYXBwX2lkCjY2Mjg1NjgzNzkAAR7TPPsVGWEzXphS59sQOUnrW8-f1HEVI3zuavDr2PlA2J0SUzLdT8qraEQ-Og_aem_Ilcu0KQ8MtHwUKfyisTeFQ)\n\n“Epigenetic clocks are powerful tools to measure biological ageing, but they are only one piece of the ageing puzzle... If a person eats a nutritionally balanced diet, many dietary supplements would probably be superfluous.” — Dr Laura Sinclair, University of Exeter.[[1]](https://www.thetimes.com/uk/healthcare/article/daily-multivitamin-slow-ageing-process-pbhtj3s9j?utm_source=fb&utm_medium=paid-social&utm_campaign=FY26_Times_Meta_AO_INTL_Performance_Conversions_ASC&utm_term=Meta_Multi_UK_AO_Multi_Advantage-Plus_Lifestyle&utm_content=pro_single_image_editorial_health_mar_mutivitamin-study-slow-aging_template-1&fbclid=IwdGRjcARBFqhleHRuA2FlbQEwAGFkaWQAAC_K2v--7nNydGMGYXBwX2lkCjY2Mjg1NjgzNzkAAR7TPPsVGWEzXphS59sQOUnrW8-f1HEVI3zuavDr2PlA2J0SUzLdT8qraEQ-Og_aem_Ilcu0KQ8MtHwUKfyisTeFQ)\n\n## Why it matters\nSlowing biological ageing markers could point to ways to ease age-related decline, though links to better healthspan remain unproven. For older adults, especially those with poor diets, a cheap daily multivitamin might offer modest cellular protection without risks. Watch for longer trials linking these changes to outcomes like cognition or disease risk, as experts urge caution on real-world impact.","hashtags":["#ageing","#health","#supplements","#science","#study","#longevity"],"sources":[{"url":"https://www.thetimes.com/uk/healthcare/article/daily-multivitamin-slow-ageing-process-pbhtj3s9j?utm_source=fb&utm_medium=paid-social&utm_campaign=FY26_Times_Meta_AO_INTL_Performance_Conversions_ASC&utm_term=Meta_Multi_UK_AO_Multi_Advantage-Plus_Lifestyle&utm_content=pro_single_image_editorial_health_mar_mutivitamin-study-slow-aging_template-1&fbclid=IwdGRjcARBFqhleHRuA2FlbQEwAGFkaWQAAC_K2v--7nNydGMGYXBwX2lkCjY2Mjg1NjgzNzkAAR7TPPsVGWEzXphS59sQOUnrW8-f1HEVI3zuavDr2PlA2J0SUzLdT8qraEQ-Og_aem_Ilcu0KQ8MtHwUKfyisTeFQ","title":"Original article"},{"url":"https://www.thetimes.com/uk/healthcare/article/daily-multivitamin-slow-ageing-process-pbhtj3s9j?utm_source=fb&utm_medium=paid-social&utm_campaign=FY26_Times_Meta_AO_INTL_Performance_Conversions_ASC&utm_term=Meta_Multi_UK_AO_Multi_Advantage-Plus_Lifestyle&utm_content=pro_single_image_editorial_health_mar_mutivitamin-study-slow-aging_template-1&fbclid=IwdGRjcARBFqhleHRuA2FlbQEwAGFkaWQAAC_K2v--7nNydGMGYXBwX2lkCjY2Mjg1NjgzNzkAAR7TPPsVGWEzXphS59sQOUnrW8-f1HEVI3zuavDr2PlA2J0SUzLdT8qraEQ-Og_aem_Ilcu0KQ8MtHwUKfyisTeFQ","title":""},{"url":"https://www.nature.com/articles/d41586-026-00741-3","title":""},{"url":"https://www.theguardian.com/science/2026/mar/09/taking-multivitamin-daily-could-help-to-slow-biological-ageing-study-suggests","title":""}],"viewCount":4,"publishedAt":"2026-04-06T22:45:22.526Z"}